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This latter variable was the most relevant surrogate we had for cooking intensity.
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Frequency at which the endpoints were chosen as first, second or third most relevant surrogates was calculated and served as final ranking.
For each cancer site and stage, final ranking of the endpoints was performed according to the frequency at which they were chosen as first, second or third most relevant potential surrogates by each participant (for complete detailed results, see additional file 3: Propositions and rankings of potential surrogate endpoints for overall survival).
Conversely, studies designed to localize the generator(s) of interictal epileptiform discharges (IEDs), the so-called irritative zone, as a putative surrogate of the SOZ will be mentioned when most relevant (for example, when validated against good independent SOZ localization information), as will studies focused on the structural or physiological substrate or sequelae of seizures.
In obese subjects, the homeostatic model assessment (HOMA2-S, a surrogate marker of whole body insulin sensitivity) was the most relevant predictive factor of the phosphocreatine-to-ATP ratio (18).
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The most relevant thing is the rise of islamophobia.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com