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It is possible that the blood compartment is not the most relevant site to detect CMV reactivation associated with the immunomodulation of donor cells.
For uveal melanoma, intrahepatic chemotherapy administration has the theoretical benefit of directly targeting the clinically most relevant site and thereby concentrating the antineoplastic activity.
The literature suggests that increased levels of hepatic iron (the liver being the most relevant site of storage) can significantly contribute to fibrogenic progression of a CLD.
Nevertheless, histologic studies of SLS skin point to the SG as the most relevant site of pathogenesis, and abnormalities in LB structure and secretion as the primary target with defective SC membrane arrays as a consequential effect.
It was suggested that secretion is the best way to transport this protein to uninfected cells to coat a surrounding uninfected tissue, which would be its most relevant site of action physiologically.
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Of the nigh-endless list of websites retrieved, 500 of the most relevant sites (selected by ranking according to their relevancy to the search terms) and specific sites that were considered interesting/helpful were evaluated by each author for their relevancy to the study purpose.
The developed framework will help, for a given marine area, to find the most relevant sites and marine technologies using multi-criteria analysis.
The motifs were ranked by the Z-score/fold change to obtain the most relevant sites [ 15].
Clinical applications generally preclude access to the most relevant sites, such as the spine and proximal femur.
The terms 'survivor'afterfter suicide'griefrief support'aftermathmand'bereaveereave' (truncated to include terms such as 'bereavement' and 'bereaved') were excluded to ensure the return of the most relevant sites.
Among the two most relevant sites of phosphorylation, tyr1068 and tyr1173, only tyr1068 was phosphorylated in LCSCs, thus increasing the relevance of this site of phosphorylation as a biomarker associated with the tumor-maintaining cells, and thus representing a potential therapeutic target for a long-lasting therapeutic inhibition.
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CEO of Professional Science Editing for Scientists @ prosciediting.com