The rates of the main and most relevant side reactions were quantified.
The hydroformylation of 1-dodecene on a rhodium-biphephos catalyst complex exploiting a thermomorphic multicomponent solvent system was studied experimentally in a batch reactor in order to describe the kinetics of the main and the most relevant side reactions.
As cardiotoxicity is the clinically most relevant side effect of anthracyclines, we extended our in vitro studies to cardiomyoblasts.
14 Daptomycin is a comparably safer antibiotic, with myotoxicity being the most relevant side effect and this can be reversed when the therapy ends.
Phase II studies of S-1 monotherapy in patients with advanced GC showed overall response rates (ORRs) of 26 49% with the most relevant side-effects being diarrhoea in a European study and neutropenia in two Japanese studies (Sakata et al, 1998; Koizumi et al, 2000; Chollet et al, 2003).
Meanwhile, distal fractures remain, at around 1% per annum, the most clinically relevant side effect of thiazolidinediones.
Haematological toxicities were the most relevant gemcitabine-related side effects observed during chemotherapy, leading to severe leukopenia (CTC, grade 3), neutropenia (CTC, grade 2) and thrombocytopenia (CTC, grade 3).
Standard immunosuppressive strategies after liver transplantation are based on steroids in combination with mycophenolic acid or calcineurin inhibitors (CNI); however their use might be associate with relevant side effects, most of all chronic renal failure, with an incidence of up to 20%% [ 1].
In effect, Google is saying, "We are not 100% sure what ads you'd like to see, so why don't you just tell us?" An ad-only search box is a departure from Google's past policy of showing the most relevant results, with ads on the side.
However, the most relevant issue with respect to potential side effects of Cr, namely the chemical purity of the Cr used, is definitely an issue (Pischel and Gastner 2007).
But perhaps art is most "relevant" when its relevance is most easily put in question?
