These 23 Hit I compounds were deemed most relevant for secondary validation assays involving a more direct test of endocrine differentiation effects, precocious 2° islet induction (Parsons et al., 2009; Rovira et al., 2011).
The expert group identified the most relevant predominant and secondary components for head and neck deviations and concurred in proposing a new multidimensional definition of response, which was based on combined aspects of efficacy and tolerability and assessment of global improvement.
If the outcome was not defined as primary or secondary, the most relevant outcome was extracted.
However, we consider that the translational potential of these findings may be most relevant for the problem of secondary pneumonia, specifically the increased susceptibility to bacterial lung infections that follows influenza.
To determine which candidates from the NIK siRNA-coupled secondary screen were most relevant in SMC-mediated cell death, we assessed protein levels of the new candidates in MDA-MB-231 cells in response to SMC treatment.
At the secondary care level the most relevant barrier found was related to the difficulties in the approval of biologics prescription.
Therefore, since in-patient stays is the most expensive component of secondary care, and in relation to LTC the most relevant, we judged hospital days to be the most appropriate measure for utilization of secondary care services.
Among the most relevant BPs identified in GSEA were those related to secondary metabolic processes, phenylpropanoid biosynthetic processes and biosynthesis and metabolism of flavonoids and indole glucosinolates.
Finally, and most relevant to the argument in this paper, primary and secondary motor and somatosensory cortices often contain voxels active during both action execution and observation/listening [ 13, 58, 60, 61].
According to this classification, the most relevant variables are the presence of TOP (5' terminal oligopyrimidines), the secondary structure, UTR length, and the existence of uAUGs [21].
