Sentence examples for most relevant receptor from inspiring English sources

For S. aureus infections, TLR2 is the most relevant receptor involved in this process.

The most relevant receptors for PNS development that we have detected in human NPs include the Sonic hedgehog receptor PTCH1, neurotrophin receptors TrkA and TrkB, and the BMP receptors BMPR1 and BMPR2, which are known to be involved, in proliferation and survival of sensory and autonomic neurons [37], [38], [39].

As mentioned above, the PAC1 receptor was proposed as the most relevant PACAP receptor in migraine partly because this is stimulated exclusively by PACAP and not, as the VPAC1 and VPAC2 receptor, also by VIP.

Both Vegfr3 and Vegfc heterozygosity most prominently resulted in a reduction of iLECs emerging between the CV and sVP, in accord with the notion that VEGF-C is the predominant VEGFR-3 ligand and VEGFR-3 the most relevant VEGF-C receptor during initial lymphangiogenesis.

Most relevant pathways were the cytokine cytokine receptor and chemokine signaling pathways, the 'Toll-like receptors' (TLRs) and the 'NOD-like receptor' signaling pathways, the 'DNA sensing' and the 'antigen processing/presentation' (Fig 2B).

The status of human epidermal growth factor receptor 2 (HER2) and the hormone receptors (HR), including estrogen receptor (ER) and progesterone receptor (PR), are the most relevant biomarkers for clinical practice, predicting response to anti-HER2 and endocrine therapies, respectively.

Most relevant studies of estrogen-related receptor alpha activity suggest that it promotes reduction of bone formation.

We have performed a standard essential dynamics (or Principal Component Analysis, PCA) analysis in order to identify the most relevant motions occurring in the receptor in the different bound states considered on the MD simulations carried out in this study (Additional file 2); all the covariance matrices have been calculated taking the apo receptor as a reference structure.

VEGF is regulated by other transmembrane receptor tyrosine kinases, the most relevant of which in breast cancer is the human epidermal growth factor receptor (HER 1 and HER2 (c-erbB-2, neu) [ 103- 105].

RAS signaling begins with the stimulation of a vast array of upstream receptors including receptor tyrosine kinases (RTKs) of which the epidermal growth factor receptor (EGFR) is perhaps most relevant to lung cancer.

Several different receptor-associated proteins have been described for the AT1 receptor, which is the most relevant mediator of the renin angiotensin system (RAS).