Additional file 1 describes the selected MGCs and updates their functional annotation whereas the following paragraphs illustrate by abundance and putative function the most relevant ones to the mussel immunity.
Together, our network biology approach provides both a high-level view on patterns in the data by identifying network modules and zooms in to the molecular level by prioritizing the most relevant nodes and interactions to identify putative targets that may aid improved therapy development.
Established pathogens were richer in genes coding for LPS, adhesion and, motility, although, the presence of capsular genes (SAP for C. fetus subspecies) and CDT were the most relevant features that distinguished established from putative pathogens (P = 0.001, Fisher's exact test).
Our second aim was to select the most relevant miRNAs that represent candidate biomarkers or putative therapeutic targets of ER+ breast cancers treated by AIs.
Serine phosphorylation appears to be the most relevant post-translational modification for TCTEX1D4, with several putative target kinases identified, supporting the relevance of its binding to the Ser/Thr phosphatase PPP1 (Fig. 1A).
Had the risk been confined to children ≥ 1 year of age, this would have indicated that any putative association with agricultural pesticides is most relevant to the sporadic form; however, we saw increased risk estimates for the group < 1 year of age and up through 9 years of age.
Conversely, studies designed to localize the generator(s) of interictal epileptiform discharges (IEDs), the so-called irritative zone, as a putative surrogate of the SOZ will be mentioned when most relevant (for example, when validated against good independent SOZ localization information), as will studies focused on the structural or physiological substrate or sequelae of seizures.
Although E. mundtii CRL1656 is phylogenetically closer to E. faecium, frequently responsible of nosocomial infections, this strain does not encode the most relevant relevant virulence factors found in the enterococcal clinical isolates and bioinformatic predictions indicate that it possesses the lowest number of putative pathogenic genes among the most representative enterococcal species.
Mathematics is the most relevant of subjects.
Which is the most relevant number?
