The most relevant grade 3 and grade 4 toxicity events were thrombocytopenia and neutropenia.
The following nonhaematological side effects were the most relevant: grade ⩾3 stomatitis was reported in nine courses, grade ⩾3 pulmonary toxicity in two, grade 3 peripheral neurotoxicity in one, grade 3 anorexia in one and psychosis in one.
Experimental demonstration of the effects of microwave energy on the product bulk density is provided for the three most industrially relevant grades of material and it is shown as to how the performance of the system is significantly better than conventional exfoliation technology, in terms of produced bulk densities, energy efficiencies, temperature of the product and plant footprint.
The latter variable is the most relevant for explaining level two variance of grade repetition.
Mucositis and gastrointestinal toxicity (i.e. diarrhoea and nausea/vomiting) were the most relevant and frequently observed grade I/II toxicities; they were generally mild and rapidly reversible.
Reversibility within a pre-determined observation period and "expectedness" are factors that are usually most relevant in the consideration of Grade 2 and non-serious Grade 3 toxicities, when decisions on study progression are being made.
Receiver operating characteristics (ROC) curve analysis of each of the DVH parameters with a P value of <0.05 in the univariate analysis was performed to select the most relevant threshold for prediction of grade 1 2 chronic GI complication.
Off air, in addition to existing targets – to have 14.2% of all BBC staff from BAME backgrounds by 2017, and 10% of those in "leadership" roles – the BBC is committing to increasing BAME staff in senior pay grades in the most relevant areas of TV and radio production, broadcast journalism, commissioning and scheduling from the current 8.3%to10%0% by 2017 and 15% by 2020.
Receiver-operating characteristics (ROC) curve analysis for each parameter was also applied to select the most relevant threshold to predict RP for grade 2 or higher.
Because tumor grade is the most relevant pathologic determinant of disease with invasive potential, these data suggest that glycoconjugates containing these antigens are associated with invasiveness in DCIS.
