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Because surveillance and effectiveness of vaccination and antiviral drugs may depend on virus lineage and specific mutations, these measures need to be evaluated in the context of viruses with the most relevant genetic and biologic properties.
Here follows descriptions of the most relevant genetic elements found in the C. pseudotuberculosis pathogenicity islands.
By systematically retrieving data from the literature, we collected frequency data for the most relevant genetic variants of NAT2 in 128 population samples representing different subsistence modes and dietary habits.
To understand the most relevant genetic features of VDAC1 overexpressing NSCLC, we conducted a gene expression meta-analysis [31], [32] to identify a subset of genes (signature) that were significantly enriched.
To this end, published frequency data on the most relevant genetic variants of NAT2 were collected from 128 population samples (14,679 individuals) representing different subsistence modes and dietary habits, allowing a thorough analysis at both a worldwide and continent scale.
Still, researchers continue to face great difficulty in identifying the most relevant genetic biomarkers for asthma.
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Objectives: Our aim was to reveal the most relevant regulatory genetic variants of the host response to elective cardiac surgery and the clinical relevance of the variants detected.
A focus on known microdeletions and microduplications makes the results most relevant to genetic counselling.
Collectively, our data provides direct evidence supporting the hypothesis that haploinsufficiency of multiple genes in the commonly deleted segment is the most likely relevant genetic consequence of deletions spanning chromosome 5q31.2.
Most medically relevant genetic variations are likely to be at low frequency (or rare) in the population.
Amplification of the ERBB2 oncogene is one of the most clinically relevant genetic changes in breast cancer and occurs in 10% to 34% of breast cancer cases.
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