Sentence examples for most relevant endpoint from inspiring English sources

Therefore, although survival, response, and QoL can all be relevant clinical trial endpoints, QoL may be the most relevant endpoint to assess in the clinic.

Future research efforts should mainly focus on experimental studies to understand how cadmium compounds could produce genotoxic/carcinogenic effects, in order to target the most relevant endpoint to be examined in humans.

However, this possible excretion pathway does not exist for air breathing animals [91, 92] and therefore bioconcentration values in fish may not be the most relevant endpoint to consider.

One can argue what is the most relevant endpoint to study, but it seems completely acceptable to us to take cost as a relevant outcome measure in the current economic situation.

While the overall net improvement in performance is perhaps the most relevant endpoint, especially in relation to patient safety, identifying the contribution of EHR skill acquisition vs. improved cognition will be essential for refinement of the activity.

16 We considered the cumulative incidence of CIN2+ as the most relevant endpoint, as it represents the threshold for treatment, and no further adjudication of the registered histology diagnoses was made.

Some of the most relevant endpoints in assessing the potential for a given protein to induce atopic or allergic asthma respiratory hypersensitivity are the development of cytotropic antibodies (IgE, IgG1), eosinophil influx into the lung, and airway hyperresponsiveness to the sensitizing protein and/or to non-antigenic stimuli (Mch).

We state that most relevant endpoints are neurological outcome and survival status at hospital discharge.

In addition, the MAC and MAC awake concept link the end-expired concentrations (FA) with the clinically two most relevant endpoints, immobility and unconsciousness.

Although increased all cause mortality was reported in a 1978 publication, 10 cardiovascular disease and coronary heart disease clinical outcomes, rather than all cause mortality, are the most relevant endpoints considered when evaluating the evidence base 25 and formulating dietary guidelines for cardiovascular risk reduction.

Importantly, there are no longitudinal data concerning the most relevant clinical endpoint of osteoporosis, fractures.