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Study Group 2A was used to determine the most relevant cutoff scores above which a tumour should be considered to overexpress EGFR for each clinicopathological feature.
To find out the most relevant cutoff point for TYRP1/S100B ratio, we divided the population into two groups according to the median, the 25th and the 75th percentiles.
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The receiver operating characteristic area under the curve was 0.69 (acceptable) at the most clinically relevant cutoff of 23.
The most clinically relevant cutoff score for TOPK was determined on subgroup A by receiver operating characteristic (ROC) curve analysis for end point survival/death.
For visualization of the most relevant subnetworks, a cutoff for the edge relevance score was identified that minimizes the complexity of the network, while keeping both the drug and module nodes connected.
As a selection criteria to present only the most relevant genes, a cutoff of a 2.0-fold increased/decreased expression and a p < 0.01 were arbitrarily chosen.
As selection criteria to present the most relevant genes, a cutoff of 1.8-fold increased/decreased expression and P < 0.01 were arbitrarily chosen.
We considered that identifying consistent trends in protein accumulation above an arbitrary cutoff such as 1.5-fold was most relevant for the purposes of discovering protein candidates for hypothesis formulation related to ripening control.
Given the large data set, the analyses described here focus on the median cutoff and continuous scale for the GBM method to identify the most relevant markers overall.
Mathematics is the most relevant of subjects.
Which is the most relevant number?
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