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Increasingly sophisticated techniques allow mutations to be introduced into specific cells to limit tumor development to the most relevant cellular source of pancreatic cancer development, the so-called cell of origin.
Our finding that MSCs may react to more carrier frequencies than differentiated cells may indicate that stem cells are the most relevant cellular model for validating safe mobile communication signals.
The replicative stress is present already in the juvenile SC, as among the most relevant cellular functions altered already at PND10 were cellular proliferation, cell death, and cell cycle according to the array.
Higher biological significance of MW effects in stem cells and apparently wider range of effective frequencies suggest that stem cells are the most relevant cellular model for assessment of health risks from mobile communication.
Our findings that stem cells are most sensitive to microwave exposure and react to more frequencies than do differentiated cells may be important for cancer risk assessment and indicate that stem cells are the most relevant cellular model for validating safe mobile communication signals.
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The most relevant molecular and cellular functions were: cellular assembly and organization, cellular growth and proliferation, cell death, and cell cycle (Supplementary Figure S4C).
At best, they have a high coverage of the most relevant relationships between cellular components, with a high percentage of correct mechanistic inferences and a low level of omission and error introduced by curation or text mining, inspector bias, and experimental error.
Using machine learning techniques we identified the most relevant aspects of cellular organization that change under evolutionary pressures.
Another study used a novel representation of metabolic networks, called a network of interacting pathways (NIP) and tried to identify the most relevant aspect of cellular organization that changes under evolutionary pressure [ 113].
To further validate our data and identify processes and cellular compartments most relevant to light and dark responses, we examined the distribution of Plant GOSlim terms within our data.
The most relevant finding is that the cellular immune response was found to have a significant influence on CBR, both in prostate cancer (OR 10.6, 95% CI 2.5 44.1) and in RCC (OR 8.4, 95% CI 1.3 53.0) (Fig. 3).
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Justyna Jupowicz-Kozak
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