Sentence examples for most relevant alterations from inspiring English sources

One of the most relevant alterations is represented by the p16 (CDKN2A -CCNDs/CDK-Rb pathway frequently altered in various types of CDKN2A -CCNDs/CDK-Rb

Diabetes mellitus is presently considered one of the most frequent diseases, therefore, it is important to know the most relevant alterations in the mouth caused by it.

DNA copy number alterations are frequently observed in ovarian cancer, but it remains a challenge to identify the most relevant alterations and the specific causal genes in those regions.

To create this model, we used E-FLLat, a dictionary learning-based method that naturally groups the most relevant alterations in elementary patterns and sorts them according to how many times such patterns occurred in the data.

Several approaches have been proposed to identify the most relevant recurrent alterations across a large number of tumor samples.

Moreover, metabolomics highlighted d-galactose, a well-known agent for senescence induction through the production of large amounts of reactive oxygen species (ROS 23, as the most relevant metabolite alteration in CCHD (47.07-fold 47.07-fold

Ovarian cancer is a heterogeneous disease displaying complex genomic alterations, and consequently, it has been difficult to determine the most relevant copy number alterations with the scale of studies to date.

The description of the alterations this network presents in association to a certain phenotype can lead to the identification of the most relevant sncRNAs driving these alterations and provide additional information to determine the sncRNAs that could have a central role in the disease.

8 The focus of this review will be on the most relevant inherited and acquired alterations in the development of breast cancer in both genders.

Here we will discuss the most relevant findings related to BM alterations in RA, focusing on their morphological characteristics and pathologic significance.

As we wanted to evaluate the most stable PTEN modifications, we considered that genomic alterations were the most relevant way to identify stable PTEN loss of function.