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The above techniques have tremendous potential in selecting the most relevant adjuvant chemotherapy.
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Therefore, the most relevant issue in adjuvant treatment now is how to improve the treatment outcome of current standard adjuvant treatment.
In melanoma, sentinel node status might be the most relevant information for selection of adjuvant therapy.
Thus, for the question of who should receive adjuvant chemotherapy, it is most relevant to identify the patients with relapse in the first 5 years after surgery.
Kennedy et al. reported that patients with TNBC who underwent adjuvant chemotherapy were 52% less likely to die compared with those who received neoadjuvant chemotherapy or no/unknown chemotherapy [ 13], suggesting that the benefit of primary tumor removal followed by early initiation of adjuvant therapy may be most relevant for the TNBC subgroup.
Further prospective studies including a larger number of patients are needed to clarify which is the most relevant time point for the evaluation of minimal residual disease before or after adjuvant chemotherapy.
Thus no patient will be prevented from accepting the best possible treatment as a complement to adjuvant chemotherapy, or in any way be omitted from receiving the most relevant treatment.
In the 190 TNBC cases of the present study, patients undergoing surgery plus adjuvant therapy had a more favorable prognosis than those receiving surgery alone, only among those with Stage II disease, suggesting that adjuvant therapy is indeed useful for TNBC patients as the NCCN recommends, and is most relevant at Stage II.
This section describes the adjuvants that have been employed during the clinical development of diverse malaria vaccine candidates, considering the most relevant vaccines and clinical trials.
Which is the most relevant number?
Mathematics is the most relevant of subjects.
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