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Most relatives indicated they preferred to order the test through their provider, rather than DTC.
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Despite the test's limitations relatives indicated interest in genetic testing (52%) while most providers indicated they would not recommend the test for their patients (79%).
Baseline survey data indicated most relatives had not heard about DTC genetic testing (61%).
Most relatives in our study indicated they had not discussed PCa genomic testing or DTC testing with their provider.
Post-focus group survey data indicated most relatives (52%) were interested in obtaining the PCa SNP test and most (56%) would prefer to order it through their provider rather than on their own.
However, while relatives may not have found testing to be helpful in making lifestyle choices (i.e., diet, exercise), most relatives in our study indicated interest in testing, both to understand genomic factors that may help with screening decision-making and also simply out of curiosity.
Figure 3 shows a large overlap between genomic islands and the regions missing in the cognate closest relative, indicating that most of the differences between these closely related strains result from horizontal gene transfer.
Most relatives had favorable attitudes toward PCa testing and indicated interest in being tested.
Most relatives (96%) found the focus group presentation was helpful and free text comments indicated it was easy to understand and informational.
Most relatives of those who died cannot.
Most cases of isolated POI still appear sporadically, but ∼10 15% has an affected first-degree relative, indicating significant genetic etiology (Van Kasteren et al., 1999).
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