Copy number loss in the short arm of chromosome 1 was recurrently observed in the LPTAs studied (29%) in agreement with most previous CGH and LOH studies of parathyroid adenomas (Cryns et al. 1995, Agarwal et al. 1998, Farnebo et al. 1999).
Moreover, homologs from individual pairs of gnathostome chromosomes were recurrently observed in interdigitated syntenic blocks on several lamprey scaffolds.
Mono- and bi-allelic deletions of PDCD1 are also recurrently observed in human T cell lymphomas with frequencies that can exceed 30%, indicating high clinical relevance.
Only mutations in ESR1, PIK3CA, and TP53 were recurrently observed in our patient cohort; thus, the analyses presented here are limited to the amplicons targeting these genes in the dPCR-SEQ panel.
Loss of the short arm of chromosome 8 has been recurrently observed in HCC.
Maritime economists as well recurrently observed the loosening economic impacts of port activities on their host cities and regions (Musso et al. 2000).
Finally, chromosomal rearrangements at 16p11.2 have been recurrently observed in several distinct developmental neuropsychiatric disorders [10], [15], [16].
The formation of amyloid-like aggregates has been recurrently observed in animal cells [1], [29], described in fungi [9] and more recently in bacteria [24], [30].
First, sudden changes disrupting the equilibrium are recurrently observed (transposition bursts, variable deleterious effects).
This suggests that the H3K36M mutation recurrently observed in HNSC patients may result in reduced levels of methylation at H3K36.
As recurrently observed in the established CAZy families, AA families have multimodular structures composed of catalytic modules associated to different ancillary modules like CBMs.
