Sentence examples for most recurrent variant from inspiring English sources

In this study, we report, for the first time, that the microRNA miR-101 is down-regulated in the most recurrent variant of pediatric soft tissue sarcoma, i.e., the embryonal rhabdomyosarcoma (eRMS), showing an inverse pattern of expression with the histone methyltransferase EZH2.

Three deleterious BRCA germline mutations have been observed in about 15% families and in about 3% non-familial breast cancer patients from North Sardinia (BRCA2 mutations were the most prevalent BRCA sequence variations and a single variant, BRCA2-8765delAG, was the most recurrent mutation with a founder effect in our population) [ 23- 25].

The BRCA1 c.916_917delTT mutation was the most represented BRCA1 variant (three positive families out of 348 cases; 1%), while the variants c.8764_8765delAG and c.3950_3952delTAGinsAT were the most recurrent mutations in BRCA2 among patients with a positive family history [13/348 (4%) and 7/347 (2%), respectively].

Memory is one of the most recurrent themes in contemporary art.

In this study, the biochemical and functional consequences prompted by a recurrent variant (R325G) found independently in four individuals with severe forms of neonatal-onset EE have been investigated.

The most recurrent theme in McEwan's 10 novels is the sudden ambush of the safe and smug.

Operative urinary sites are the most recurrent infections.

Usually, most recurrent liver disease was detected by computed tomography.

Cutaneous CD30+ LPD is an indolent, recurrent variant of CTCL that has been shown to be radiosensitive.

For 127 catastrophic Mendelian diseases (those caused by a single gene such as cystic fibrosis and ataxia-telangiectasia), there are presently 164 genes harboring 685 known recurrent variants that are highly penetrant and causal for deleterious traits, most typically manifesting in individuals before the age of 18 (18.

The exclamation mark '!' designates back mutation and recurrent variants are underlined.