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It lacks access to the most recent virus research information.
Interestingly, one of the most recent virus isolates (sample ID: H5 2007007) isolated in 2007, was closely related to the vaccine strain and early virus isolates.
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We have thus developed a processing pipeline and browser-based visualization that allows convenient exploration and analysis of the most recent influenza virus sequence data.
There were over 100 sequences of each protein of every virus with exceptions for the most recent human viruses, H1N2 and H5N1, and the PB1-F2 protein.
For many years, the seasonal vaccine has been comprised of three of the most common circulating influenza viruses, A(H1N1), A(H3N2) and B. Consequent to antigenic drift and assumption of limited cross-reactivity of antibodies against strains that are significantly different from the older strains, the virus strains included in the vaccine are "updated" to the most recent circulating viruses.
This is especially true of the human H1N2 virus, the most recent human influenza A virus.
Hemagglutinin of influenza A(H7N9) virus belongs to clade A. Genetic data indicate that the most recent ancestral wild bird origin virus for A/Hangzhou/1/2013(H7N9) virus and Zhejiang domestic duck viruses can be dated to 2004.
These genotypes co-circulated in Peru in 2006 and 2007; however, the most recent influenza B virus isolates from 2008 belong to the B/Florida/04/06 genotype, which also includes the vaccine strain for the Southern Hemisphere (Figure 6).
Phylogenetic comparisons of HA and NA genes showed that the sequences of most recent European influenza viruses A (H1N1) fell within clade 2B, represented by A/Brisbane/59/2007, the recently recommended vaccine virus for 2008 09.
There was no apparent segregation of the viruses in the two most recent clades of Myanmar viruses according to the township (suburb) where the patient lived or to the date of onset of symptoms, i.e., viruses from both clades appeared to be co-circulating.
In the most recent outbreaks of H5N1 virus, some of these peptides are conserved in viruses isolated from human patients (Table).
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