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Her most recent creatinine value was 315 umol/L (March 2013).
Baseline creatinine was defined as the most recent creatinine measurement from an outpatient clinic or general practitioner in the period from one year to seven days before the current hospitalization [ 19].
We defined the baseline creatinine level as the most recent creatinine measurement from an outpatient clinic or general practitioner visit in the period from one year to seven days before the current hospitalization [ 26].
Patients are excluded from the study if they are less than 30 years of age, their most recent creatinine is greater than 1.5 mg/dl, they have class III or IV heart failure, their life expectancy is less than one year or they have reduced cognitive capacity as determined by the patient's PCP.
To reduce misclassification of eGFR from variability in serum creatinine results or acute illness, we used a last-carried-forward method, with eGFR initially defined using the creatinine result that marked entry to the study and updated at each subsequent creatinine result so that eGFR was always defined by the single most recent creatinine result, as previously performed by James et al.
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Perioperative AKI was defined according to the criteria of The Society of Thoracic Surgeons (STS) as an increase in creatinine > 2.0 (mg/dl), a 100% increase from the most recent preoperative creatinine level, or need for dialysis [ 15].
The most recent serum creatinine was normal at 41 μmol/L (eGFR 94 mL/min/1.73 m).
We chose the most recent serum creatinine value from any setting prior to the outpatient prescription as our test value.
If a patient is still in hospital beyond 14 days, the most recent serum creatinine value performed in routine care prior to the hospital discharge is also recorded.
We used the most recent plasma creatinine measurement from an outpatient clinic or general practitioner one year to seven days before the current hospitalization to compute eGFR [ 19].
We therefore used the most recent serum creatinine concentration before admission for emergency patients to distinguish chronic kidney disease from preoperative acute kidney injury.
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