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The inhibitory effect we observed is most readily explained by α-Syn amyloid binding to PrPC on the cell surface, which blocks the docking of PrPSc template for further replication.
Therefore the negative potential in the normal recording medium is most readily explained by active net uptake of sodium (Figure 3C).
As antibodies cannot diffuse through the cell membrane, this finding is most readily explained by the endocytosis of ACT, suggesting that once bound to the cell, the toxin may be internalised.
Specifically, differences between amino acids 4 56 are most readily explained by incorrect sequences generated in GC rich areas.
This is also most readily explained if the inhibitor binds to MCT1 and MCT2 exclusively from the intracellular side.
In summary, these results are most readily explained by a Wahlund effect due to pooling of the samples from the structured, contemporary population [ 27].
Similar(42)
It has also been suggested that the brain may seek to derive the "generative model" [e.g., Friston, 2005] that can most readily explain and even predict sensory observations.
This need for role play, this desire to create a simulacra of the wild behind glass in an Indianapolis mansion, is interesting, but like most everything not readily explained in a series of slides it goes unexplored by Packer.
They are planar in form, truncate a wide variety of bedrock types, and can most readily be explained by scarp retreat under non-vegetated conditions.
In a commentary in Nature, Dr. Len A. Fisk, a space scientist at the University of Michigan who is not involved with the two research teams, said he tended to agree with the Krimigis team's argument that the "data can most readily be explained if the termination shock has been crossed".
This increase in C G transitions can most readily be explained by replication of dU G lesions that were no longer detected and processed by the missing MMR proteins to introduce C-to-T or G-to-A mutations (Figure 5).
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