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Comparative gene expression profile analysis of patient-matched normal versus ADH, normal versus DCIS, and normal versus IDC revealed that the most pronounced transcriptome change occurred at the normal to ADH transition, and that such transcriptional alterations are maintained throughout the later stages (DCIS and IDC) of progression.
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We first identify that components of the ribosome, cell adhesion and immune response are among the most pronounced differences between the transcriptomes.
We report on the most pronounced processes in the maternally transferred cod transcriptome.
Thus, similar to the age-dependent changes that we observed in miRNA expression, we found that the CD8+ T-cell transcriptome also exhibited the most pronounced age-dependent changes in naive cells, rather than effector cells at any stage of the primary immune response.
Analysis of the transcriptome of TIGR4 and G54 revealed the following biological themes as being the most pronounced: G enes encoding cellular processes.
This is most pronounced for BW, with 18% of explained variance from the genome and 63% from the liver transcriptome.
To substantiate Brachyury-dependent down- and upregulation, respectively, of mesoderm-specific and neurogenic genes, control and Xbra/Xbra3 knockdown embryos were subjected to transcriptome-wide profiling (RNA-seq) at the early tadpole stage, when the knockdown phenotype was most pronounced and RT-qPCR suggested that transcriptional misregulation might be most dramatic.
The trend is most pronounced in Germany.
The Honda's evolution is most pronounced inside.
But it is most pronounced at the post-secondary level.
Segregation of Latino students is most pronounced in California, New York and Texas.
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CEO of Professional Science Editing for Scientists @ prosciediting.com