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The most promising parameters for a large NOX reduction and a low fuel penalty have been applied in the dosing strategy and tested in an ETC.
Nevertheless, nCD64 is one of the most promising parameters.
It also supports RI and SF as the most promising parameters to evaluate for early treatment response during RT.
To guide such a therapy, the most promising parameters appear to be plasma levels of procalcitonin (PCT) [ 4].
Mitotic index and Ki67 staining are the most promising parameters; however, results for these markers are controversial (Begg et al, 1999; Daniels et al, 2002; Caly et al, 2004; Jalava et al, 2006).
Nevertheless, the detection of DTC in bone marrow and blood has become one of the most promising parameters for identifying high-risk breast cancer patients – and may, moreover, allow monitoring of patients under therapy in order to determine the therapy response in the future.
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Finally, self-adaptive control refers to techniques in which parameters are directly encoded in individuals with the aim of allowing evolution to identify the most promising parameter states.
Once the most promising parameter changes have been identified, realistic designs can be produced accounting for practical constraints of the railway environment.
This behaviour was expected, since, like any other adaptive parameter control method, BNGA needs to identify the most promising parameter states, whereas the static approach takes advantage of "off-line tuning".
For the most promising parameter set (F = 0.8, λ = 0.5, and CR = 0.3 for GMAKr and GMMr, and CR = 0.9 for the CKMMr), the population size is additionally varied over {50, 250, 500, 1000} for each model.
With the most promising FISH parameters selected and their optimal cutoffs derived from the log-rank test, a multivariate Cox proportional hazard model was used to select the final FISH parameters after adjusting for key clinical factors (age, gender, tumour grade and stage).
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