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However, RVD has shown the most promising effect.
In restoration of CHL toward normalization chloroform extract (100 mg/dL) showed the most promising effect.
Disease-modifying agents are still in development and to date, antioxidant α-lipoic acid has shown the most promising effect.
This mechanism will need to be determined as we observed the most promising effect with combination treatment of cisplatin with Src or JNK inhibition.
Among the five extracts, the most promising effect was observed in case of chloroform and ethyl acetate fractions followed by petroleum ether fraction exerted a significant decrease of licking time in both phases.
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The most promising effects were observed in the double mutant V81P/G82E.
The interventions that demonstrated the most promising effects tended to provide customized supports to more narrowly targeted subgroups, particularly younger persons and those with psychiatric impairments.
In general, the interventions that demonstrated the most promising effects tended to provide customized supports to more narrowly targeted subgroups, in particular, younger persons and those with psychiatric impairments.
Furthermore, ligands 2 and 5 with the most promising effects on human α1-GLYRs were examined for their toxicity and potential neuroprotective effect against neurotoxin 6-hydroxydopamine (6-OHDA).
Among them 13-1-e shows the most promising effects on the zebrafish embryonic growth, the selective inhibition of cyclin E/CDK2 kinase activity, and the prevention of tumor cell proliferation in vitro and tumor size in vivo.
In ALS, the most promising effects of melatonin are those of blocking apoptotic pathways and reducing oxidative damage.
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