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The most promising agents had higher inhibitory potency than the reference drugs which was tacrine.
To discuss potential candidate chemoprevention agents with an emphasis on the lipid lowering drugs, the statins, currently, the most promising agents.
Finally, coordination and concentration of future research on the most promising agents will be necessary in order to accelerate the search for neuroprotective therapies in PD.
The biological activity of the most promising agents was further evaluated in vitro by electron microscopy and in vivo in a Galleria mellonella model of C. albicans infection.
The most promising agents developed and tested were small molecule tyrosine kinase inhibitors, mammalian target of rapamycin inhibitors and monoclonal antibodies.
The potency and selectivity demonstrated by these compounds are dependent on the cancer cell line, where the following compounds were found the most promising agents against certain cell lines: compounds 1i and 1j for HL-60 cells, 1a and 1b on HCT116 cells, 1f on Hela cells and 2h on H1975 cells.
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TD-5471 (25), a potent and selective full agonist of the human β2-adrenoceptor, was identified as the most promising agent.
Currently, annexin V is considered to be the most promising agent in clinical applications [ 44].
Therefore, ATRA is the most promising agent to enhance the antitumor activity of TPT in AML.
According to these studies, the antibiotic agent of azithromycin was suggested as the most promising agent for treatment of patients with SAPHO syndrome.
According to Table 2, compound OC-2 was the most promising agent against multiresistant bacteria, with MIC values ranging from 15.60 to 31.25 μg mL−1 for a large number of tested microorganisms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com