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The most prominent weakness of "Jackson's Dilemma," for me, lies with the eponymous Jackson; one of Murdoch's many spoiled priests, wistful for faith but not secure in it, he has no clear role (or dilemma) among the restless and self-indulgent English élite as they impulsively, wastefully shuttle from country home to London and back.
This constitutes possibly the most prominent weakness of the available studies in PBC genetics, as the candidate genes were often chosen based on a weak background.
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This study was carried out in an attempt to overcome the two most prominent weaknesses of the organised screening, the non-optimal participation rate and the relatively low sensitivity of cytology.
Others say it is only a matter of time before the rivalries between the coalition's most prominent leaders — and their weaknesses — begin to surface again.
Proximal SMA is characterized by muscular hypotonia, hyporeflexia, and general weakness, which are most prominent in proximal muscles with prevalence of the lower extremities.
Research in this field has been hampered by methodological weaknesses, whereof the most prominent has been sampling bias.
Weakness was reported as the most prominent somatic symptom by the total sample (Table 3 upper panel).
Muscle weakness was found to be most prominent in proximal limb muscles, while facial, eye, and bulbar muscles are largely spared.
The most prominent clinical phenotype common to these families is progressive weakness and spasticity, affecting the lower extremities, plus or minus the upper extremities.
Similar to the cholera vignette, weakness was also rated as the most prominent somatic symptom for the shigellosis vignette (Table 6 top panel).
A child affected by kubemenda could be recognized as it presented with different symptoms, the most prominent ones being frequent diarrhoea, malnutrition, abnormal thinness, poor growth, weak upper and lower limbs, generalised body weakness or paralysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com