Sentence examples for most prominent pathways from inspiring English sources
The best characterized and the most prominent pathways leading to apoptosis are called the extrinsic and intrinsic pathways.
Also, 33 pathways were identified (P < 0.05, Additional file 10), and the most prominent pathways among them were regulation of actin cytoskeleton, MAPK signalling pathway, and tight junction.
Immunosuppression or induction of reactive oxygen species via inflammatory reactions have been suggested as the two most prominent pathways for indirect infectious carcinogens.
In contrast, some of the most prominent pathways that correlated with the antagonists include growth factor receptor signaling pathways consistent with the growth promoting activity assigned to these miRNAs.
However, the most prominent pathways are related to oxidative stress, mitochondrial electron transport chain, vacuolar acidification, regulation of macroautophagy associated with protein target to vacuole, cellular response to starvation, and negative regulation of transcription from RNA polymerase II promoter.
Given the extreme genomic instability which is notorious in osteosarcoma and has led to the formulation of a novel genetic mechanism, chromothripsis [ 32], it is not surprising that the most prominent pathways are associated with this signature.
The most prominent pathway responsible for maintaining extracellular LPA levels in the circulation stems from the action of the lysoPLD known as autotaxin, an enzyme intimately associated with the progression of tumors and metastasis [8].
The most prominent pathway involved in RAS-mediated apoptosis is the Raf ERK pathway.
These findings apparently confirm that the degradation pathway through NOT1 in Figure 1 is the most prominent pathway for degradation of the target mRNA.
Of these, a granulocyte adhesion and diapedesis-associated gene signature was the most prominent pathway affected in the various 4T1-derived explants.
Looking on a pathway level using the KEGG classification we found the MAPK signalling pathway as the most prominent pathway in our dataset with a total of 33 kinases including 14 candidate clients[ 24].
