Pathway analyses inferred a functional connection among 35 of these genes in one major network, with TNF as the most prominent node.
We have identified, for the first time, that TNF is the most prominent node in a network of Cd-regulated genes related to immunomodulations, oncogenesis, cell proliferation, and apoptosis.
Briefly, clique percolation is the most prominent overlapping node clustering algorithm, greedy modularity optimization is the most popular modularity-based technique, and Infomap is often considered the most accurate method available (Ahn et al., 2010).
When tumour-transplanted mice were sacrificed due to overt CLL, we again observed a trend for increased CD274 levels, which was most prominent on lymph node-residing CLL cells (Fig 2; MFIR 17·2 ± 17·1, P = 0·003).
Postmortem examinations showed hemorrhages in multiple edematously enlarged lymph nodes, most prominent pulmonary hyperemia and alveolar edema, hyperplasia of the mesenteric lymph nodes, and acute gastritis with hemorrhages.
One of the most prominent characteristics of a node in a network is its degree, or number of neighbors.
Results: This study demonstrated that increased CD34+ cell levels were most prominent in patients who were node positive and patients with recurrent disease.
Objectives: This study determined whether mobilization of immune inhibitory CD34+ cells by head and neck squamous cell carcinomas (HNSCC) is most prominent in patients who are node positive and whether these CD34+ cells could differentiate into immune stimulatory dendritic cells.
From this extraction we selected all basal readouts and 12 of the most prominent response readouts representing responsive signaling nodes.
Axillary lymph node status, the most prominent prognostic factor in breast cancer, was not significantly different between the two groups.
