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The most effective drugs have tended to have the most profound effects on the immune system, which can result in treatment-limiting adverse events [ 5].
Results indicate that the glycyl derivative of oseltamivir has the most profound effects on the membrane, compared to other derivatives and seems to be the most promising derivative for further pharmacological evaluation as a neuraminidase inhibitor.
The Conservative economic line at the time – that austerity was the way out of recession and that spending should be reduced across the board – had its most profound effects on welfare, healthcare, housing and the pillars of our society, but the arts were to be slashed as well.
This has the most profound effects on public safety, politics, education and health ., says Zichermann. - The best-gamified solution you have seen so far?
Mineral deficiencies appear to have some of the most profound effects on lead toxicity, since the consequences of plumbism can be exaggerated by feeding diets low in calcium, phosphorus, iron, zinc, and in some cases, copper.
The most profound effects on gene expression profiles in breast cancer are related to estrogen (ER), and proliferation status, and to a lesser extent to Human Epidermal Growth Factor Receptor 2 (HER2) status.
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The most profound effects of antimicrobials on the intestinal microbiota were observed immediately after treatment (Day 5), which is in agreement with reports in humans [ 20, 27] and horses [ 15].
Yet some of the most profound effects of loneliness are on the mind.
"This will have the most profound effect on the Israeli public.
The bye week may have had its most profound effect on Beasley.
These movements had the most profound effect on social and political life, permanently altering the beliefs by which men live.
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CEO of Professional Science Editing for Scientists @ prosciediting.com