Sentence examples for most profound decrease from inspiring English sources

The most profound decrease was observed in NK cells.

For 14, all alanine analogues were less active than the original peptide; however, the exchanges W3A, G7A, and Y8A led to the most profound decrease in activity, indicating that these residues form a conformational binding epitope for interaction with KDM4C.

The number of CD4+ and CD8+ T cells, B cells and NK cells all decreased during dosing with the NK cells showing the most profound decrease, whereas monocytes increased (Fig.  2c).

The trend of the mRNA expression ratio of FOXP3 to MAN1A1 was similar to that of the FOXP3 expression; the ratio decreased on day 7 in all groups, with the most profound decrease and subsequent increase towards pre-KTx levels being seen in the rATG group.

Similar to the findings for CD247, GZMB, and PRF1, the mRNA expression of FOXP3 was decreased in all groups on day 7 compared to the pre-KTx level with the most profound decrease and subsequent increase towards the pre-KTx level in the rATG group.

The most profound decreases are seen in subcortical areas, such as the nucleus accumbens, putamen and the midbrain, while cortical areas show smaller decreases, and even a tendency towards increases in some prefrontal areas.

One of the most profound changes is a decrease in the percentage of time spent in slow-wave sleep (stage 3), as characterized by a reduction in the number and amplitude of delta waves.

Following IR, HCT116 cells were shown to have a time-dependent HIF1 α protein decrease, which was most profound at recovery, and therefore antithetically followed p53 protein expression.

The most profound promoting effect was exhibited by H2, which decreased MPO temperature by 50 520 °C, at which unpromoted MPO gave no products.

The rapid and profound decrease in smoking is probably the single most important factor.

In Los Angeles, perhaps the most profound change automation has the potential to bring is a decreased need for parking spaces.