The grave effects of internal emitters are of the most profound concern at Fukushima.
In April 2010, 171 researchers sent a letter to Francis Collins decrying the bill and expressing their "most profound concern about the impending loss of chimpanzees".
What might be their most profound worry?
The Jewish philosopher Martin Buber spoke directly to the most profound human concerns in all his works, including his discussions of Hasidism, a mystical-religious movement founded in Eastern Europe by Israel ben Eliezer, called the Baal-Shem (the Master of God's Name).
Beatrice's first and most profound shock concerns her father, Dr. Jeremy Fisher-Harthethe "whole, seamless tapestry" of her life torn and rendered "incoherent" by her discovery that he has sexually harassed his clients and the graduate students who revere him.
The great tympanums (the space above the lintel of a door that is enclosed by the doorway arch) of Autun, Moissac, and other medieval churches symbolize some of the most profound Christian doctrines concerning the ends of human life and man's relations with the divine.
The moment when, if you return to your beginning, to quote T.S. Eliot in probably one of the most profound statements ever made concerning the arts, you will find "the end of all our exploring will be to arrive where we started and know the place for the first time".
What does concern him is, in the most profound sense, a mystery -- or maybe the mystery, since the subject of "Silent Light" seems to be nothing other than existence itself.
Insofar as it does this, it will express his most profound sense of values and thus be likely to concern itself with matters of more permanent significance than topical issues.
As Turner and Isenberg make clear, the conservative abdication of environmental concern stands out as one of the most profound turnabouts in modern American political history, critical to our understanding of the GOP's modern success.
