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Some of the most profound changes have been less visible.
This was the year British television underwent one of the most profound changes in its history.
It will be one of the most profound changes in our 184-year history.
"We are rebuilding ourselves in some of the most profound changes I've seen," Ms. Whitman said in an interview.
That is all very well, say Labour supporters, but the most profound changes are agreed among states in international forums.
The procedural confusion only highlighted how backdoor the Senate's approach has become to one of the most profound changes in a generation to America's security commitments in Europe.
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What has been the most profound change?
"But it is probably the most profound change that colleges have seen since the G.I. Bill".
Perhaps the most profound change is in the perceived achievability of Make Poverty History's mission.
But the most profound change was in how the pollsters selected the people they questioned.
The most profound change in a cellular economy is the devaluation of the transaction.
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most modest changes
most evident changes
most notorious changes
most profound movements
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com