Sentence examples for most profound challenge from inspiring English sources

Climate change represents the most profound challenge humanity has ever collectively faced.

Perhaps the most profound challenge to religion came with Charles Darwin's On the Origin of Species (1859).

The government's "reinterpretation" is the most profound challenge to the pacifist constitution since 1947.Mr Abe faces, however, one serious roadblock: the constitution's popularity.

The disputed election last summer and the government's reaction was a catalyst for the most profound challenge to the ruling establishment in its entire history.

The officers, including many reservists, were the lawyers, doctors, teachers and intellectuals who would have posed the most profound challenge to the cynical division of Poland under the Hitler-Stalin pact of 1939.

If society gets serious about controlling greenhouse-gas emissions, this would be the most profound challenge to the structure of our energy supply, because that supply is based on fossil fuel.

Environmental dilemmas are among the most profound challenges facing humanity.

Managing migration is one of the most profound challenges for international cooperation in our time.

The controversies surrounding peer-to-peer file distribution present one of the most profound challenges to copyright law to date.

The quest to achieve genuine equality and inclusivity is one of our society's greatest and most profound challenges.

Well into the seventeenth century, the most profound challenges to Indian life came less from the arrival of a relative handful of European colonists than from the biological, economic, and environmental forces the newcomers unleashed.