Sentence examples for most probably functionally from inspiring English sources
More importantly, PPGs are most probably functionally different from PSA, owing to their very long (often more than 1000 residues) serine-rich stretches on which are anchored very large amounts of phosphoglycan chains [ 5].
Although the missense variant present in ISO12 (M45I; detected in 38%% of the mapped alleles) is most probably functionally active, the effect of such amino acid change on the decreased respiratory capacity of ISO12 (by direct effects on CYC3p or through epigenetic mechanisms) cannot be discarded [ 78].
As our analysis revealed that mutations at MLK3 are most probably functionally relevant, occurring almost exclusively in MSI carcinomas, and that MLK3 is described as a component of the multiprotein BRAF/RAF1 complex (7, 9, 10, 20), we decided to analyse how mutations in MLK3 (all types) correlated with mutations in KRAS and/or BRAF in our series (Table 2 and Fig. 5).
Although not significant, in the kidney our results show a trend of up-regulation for both of these ATPases known to be inhibited by metals, particularly for the most highly expressed (and therefore probably functionally most important) isoforms in this tissue.
Most probably, a complex functionally defined signature would consist in a meta-signature that has been built by taking into account several functional aspects of metastasis.
In patients with coronary artery disease angiotensin-converting enzyme (ACE) inhibitors reduce cardiovascular mortality and myocardial infarction rate, most probably by producing beneficial action on functionally damaged endothelial cells and by reversing atherosclerotic process to some point.
Gray rows indicate mutations evaluated as probably functionally damaging by our own knowledge-driven functional assessment.
This result shows that pathway-level analysis of microarrays is able to provide a functionally coherent and highly efficient prognosis classifier, which will most probably be more stable than the classifiers from which it originates.
Thus, during the teenage years, subjects with structurally and functionally defective epithelium and earlier exposure to allergens, infections and pollutants most probably have evidence of persistent activation of EMTU with evidence of remodelling, leading to persistent asthma.
In higher plants, duplication of the ancestral bch gene took place most probably via whole-genome or segmental genome duplication [ 26] and the duplicates seem to have functionally diverged primarily at the gene expression level [ 60- 62].
