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The medium- to long-term perspective that the scenario method brings into the discussion most probably facilitates the inclusion of supporting and final values as the focus is in a story instead of in a snapshot (which would be favoring only the final values).
The structure of the TmCorA loop reveals that the negatively charged Glu faces towards the concavity, and most probably facilitates the initial trawling of Mg2+ ions, as predicted previously [ 15]. Biochemical studies as well as molecular dynamics simulations have suggested Glu to be the main binding and selection site for a fully hydrated Mg2+ [ 21, 22].
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Most probably, CD24 facilitates intravasation of tumour cells (Kristiansen et al, 2002; Kristiansen et al, 2003a, 2003b, 2003c; Kristiansen et al, 2004).
This might provide helpful information for the development of new biocatalysts and, most probably, will facilitate drug metabolite prediction in pharmaceutical research and development.
In contrast, binding of Ang-2 to Tie2 disrupts protective Ang-1 signaling and facilitates endothelial inflammation, most probably via preventing Ang-1 from phosphorylating Tie2 [ 4].
PPP1CC is known to bind to and dephosphorylate the IC (Whyte et al., 2008), and most probably PPP1 binding to TCTEX1D4 would facilitate its access and binding to the IC.
The cubane cluster thus facilitates ET from Fed to O2, most probably through purely electrostatic interactions.
In contrast, when the gene is frequently hypermethylated in hESCs, it most probably becomes selectively demethylated upon differentiation as an epigenetic mechanism that is able to facilitate tissue specification.
Upon exposure to an alkylating agent, the recruited Rad51 facilitates DNA synthesis on a damaged template in a DSB repair-independent process, most probably by promoting gap filling of single-stranded lesions that accumulate during replication of alkylated DNA.
These changes in morphology of the endothelium facilitate the subsequent infiltration of blood cells and their accumulation in the space of Disse, and most probably represent an early event in the pathogenesis of paracetamol-induced liver injury.
Most probably.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com