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The paralogous genes evolved due to the development of new function and provided the most probable role for adaptation.
The genes with assigned function were grouped into functional categories using the Arabidopsis thaliana Munich Information Centre for Protein Sequences (MIPS) database, and suppression of redundancy in MIPS funcat assignations by decision according to their most probable role in xylem development (Additional file 3).
Similar(57)
Therefore, it differs from OncodriveROLE, designed to classify previously identified driver genes into their most probable roles.
Additionally, although homology search (e.g., best BLAST hit) can be a poor surrogate for the taxonomic identity of a given fragment, learning the most probable functional role of an encoded gene can help to provide a measure of confidence in the predicted assignment.
The control of calcium homeostasis is the most probable nongenomic function of platelet VDR, given the important role of calcium fluxes in platelets formation, aggregation and granule content release.
In this experimental model the most probable candidate to the role of tumor microenvironment cells is CD 117+.
We think the most probable reason is that the role of L-AA is not so specific.
We report the probability of the most probable path for each of the equally probable gene segment sets.
This result supported the role of CHT as the most probable responsible for the brain hypometabolism in our sample.
IFNG, one of the most probable upstream regulators, is known for its paramount role in acute rejection.
Although our results tend to suggest a more probable role of hybridization as the most likely explanation for the major incongruence between two trees, incomplete lineage sorting and introgression cannot be completely excluded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com