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Depending on the MAF at the locus and the genotypic configuration of the MGS, Sire and Offspring, the most probable genotype from Single_Step method may still be associated with a posterior probability that is higher than could be inferred based on haplotype frequencies alone.
Bam2mpg was used to implement the Most Probable Genotype (MPG) algorithm, a Bayesian based method to determine the probability of each genotype given the data observed at that position.
For the parents' genotypes, we used the most probable genotype determined by the phasing tool (10).
Genotypes were determined using a Bayesian algorithm, Most Probable Genotype (MPG) [ 22].
The individuals were then classified according to the most probable genotype (i.e. HH, HL or LL) for each locus.
21, 22 Conversely, GATK and SAMtools compute the Bayesian genotype likelihood to infer the most probable genotype.
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The most probable genotypes of inferred fathers were used for further statistical analysis.
To be able to inspect LD structures and also for gene-level analyses, allele dosages of imputed SNPs had to be converted into the most probable genotypes.
Values for allele frequency of each haplotype within the nineteen genotypes are based on the model for the most probable genotypes (Table 5) with a maximum of seventy-six possible alleles in this sub-population (100%).
Following assumptions of Mangin et al. [ 29], only the most probable sire genotype was considered and retained to compute the likelihood, whereas all dam genotypes with probability higher than 10% were considered.
Based on the dynamics of the CBN, this strategy selects the most probable hidden genotype.
More suggestions(14)
most virulent genotype
most common genotype
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most important genotype
most prevalent genotype
most susceptible genotype
most frequent genotype
most homogeneous genotype
most resistant genotype
most favorable genotype
most observed genotype
most tolerant genotype
most likely genotype
most predominant genotype
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