Sentence examples for most prevalent polymorphism from inspiring English sources

Atg16L1 did not localize to the plasma membrane upon expression of Nod2fs (the most prevalent polymorphism in Crohn's disease) (Travassos et al., 2010), suggesting that sequestration of Atg16L1 by Nod2fs in the cytoplasm interferes with the autophagosomal delivery of the bacteria.

While single nucleotide polymorphisms (SNPs) represent the most prevalent category of polymorphisms available within the genome, few studies have developed and mapped SNPs in cotton [ 14, 19].

Two "privileged fragments", caffeic acid and piperazine, were integrated into bevirimat producing new derivatives with improved activity against HIV-1/NL4-3 aNL4-3/V370A70A carrying the most prevalent bevirimat-resistant polymorphism.

The most prevalent single nucleotide polymorphism (SNP) for human MnSOD leads to the replacement of valine at position 16 in the human enzyme to alanine.

Compound 6 was at least 20-fold more potent than 1 against the replication of NL4-3/V370A, whicarriesies the most prevalent clinical BVM-R polymorphism in HIV-1 Gag-SP1.

These polymorphisms are most prevalent in southern Europe.

In our study, heterozygosity for c.151+1G>T that leads to one null allele had no impact on LS-BMD, while neither of the most prevalent variants, c.1513A>C, nor c.1729T>A polymorphisms alone showed any significant decrease in LS BMD at either the first or the follow-up visit in our cohort, consistent with the previous report of Ohlendorff et al (Tables 2 and 3).

Concisely, the system combines ligation-mediated amplification with the detection of amplified products on a microarray to detect the various carbapenemase genes: OXA-48, NDM-1, IMP, VIM, and KPC; CTX-M groups: CTX-M group 1, 2, 9 or combined 8/25; and the most prevalent ESBL-associated single-nucleotide polymorphisms in TEM and SHV-variants.

The majority of these polymorphisms occurred at position 58 in NS5A GT4d sequences, and the T58P polymorphism was the most prevalent, being present in 70.6% (48/68) of the GT4d samples.

These results contrast with those of Chang et al, 10 who argue that the DRD4-IIIe-7r polymorphism is the most prevalent one in Native Americans; but in all other regards our results are similar to reports on European populations.

Baseline polymorphisms, including the most prevalent E157Q analyzed separately, were not associated with the virologic failure on RAL [p=0.5, OR 1.56 (95% CI: 0.35-7.11) and p=0.38, OR 1.83 (95% CI 0.38-10.05), respectively].