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Two of the most prevalent functional classes that show clear function-expression coherence are genes involved in sexual reproduction and host immune response.
Protein metabolism and modification, and nucleic acid metabolism are the most prevalent functional processes in cancer.
Thus, the S-helix represents one of the most prevalent functional themes involved in the flow of signals between modules in diverse prokaryote-type multi-domain signaling proteins.
The most prevalent functional categories among the modulated genes were metabolic process (25.6% and 19.4%, respectively) and signal transduction (11.5% and 14.5%, respectively) for both maize lines.
Many transcriptional changes occurred solely in V. riparia, and the most prevalent functional categories among the modulated transcripts were general metabolism and signal transduction, the latter especially at 12 h.
Amino acid transport and metabolism, as well as nucleotide metabolism, were among the most prevalent functional categories up-regulated during early embryogenesis, but showed a gradual decrease at subsequent stages of development (profiles 1 and 6).
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Most prevalent in the functional domain were impaired routine daily activities and impaired leisure activities (just above 80%), which were unbearable in half of the patients.
The most prevalent over-represented functional categories among female-upregulated genes are those involved in development, including tissue development, neurogenesis and nervous system development (Additional file 8: Table S6).
All-cause mortality was most prevalent in the total functional capacity low-score group, more prevalent in the middle-score group, and least prevalent in the high-score group (Table 2).
To test the possible overrepresentation of LQTS-associated variants in ESP we genotyped the four most prevalent LQTS-associated variants with significant functional effects present in ESP in two cohorts of healthy individuals with available ECGs.
In addition, a PolyPhen-2 prediction was conducted, and the four most prevalent LQTS-associated variants with significant functional effects present in ESP were genotyped in a second control population.
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