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Here, we highlight the potential of miRNAs for the engineering of Chinese hamster ovary (CHO) cells, these being the most prevalent cell factory system for biopharmaceutical production.
Previous work in our lab has found that photopolymerizable HA hydrogels are suitable scaffolds for the culture and proliferation of valvular interstitial cells (VICs), the most prevalent cell type in native heart valves.
SpA is one of the most prevalent cell wall proteins on S. aureus and appears to play an important role in the success of S. aureus as a human pathogen [10]; [10].
When all patients were considered, macrophages were the most prevalent cell type, followed closely by lymphocytes and neutrophils.
In the healthy heart, cardiac fibroblasts are the most prevalent cell type, accounting for up to 70% of cells, depending on the species in question [ 1, 2].
Myofibroblasts are not normally found in the healthy myocardium, but are the most prevalent cell type in the infarct scar and are the main effectors of fibrogenesis [ 10].
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For primary cell interactions, macrophages represent the most prevalent cell-type, although less than 200 interactions have been recorded.
Alveolar macrophages were the most prevalent cells in BALF (> 95%) from healthy subjects or transplant recipients who did not have distal bronchoalveolar inflammation (neutrophils in BAL cell differential counts <4%).
The most prevalent inflammatory cell type in BTC was the T lymphocyte.
In BTC, T lymphocytes were the most prevalent inflammatory cell type (for exemplary photomicrographs, see Supplementary Figure 1).
Medium-sized spiny projection neurons are the most prevalent neuronal cell type in both the dorsal and ventral striatum, by far outnumbering the smaller and heterogeneous population of striatal interneurons.
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