The most predominant subtypes were 3a (38%) and 1b (26.8%).
The three top predominant subtypes observed in Zhenjiang are also the most predominant subtypes in Xinjiang and Yunnan (Fig. 2).
Currently, 4 HCV genotypes (1, 2, 3 and 6) including more than 13 subtypes are prevalent in China, and the two most predominant subtypes are 1b and 2a, both which result in a nation-wide prevalence [2], [25].
In addition, subtypes 1a, 1b, 3a, 3b, 6a, 6n, and 6u are circulating among IDUs, with the most predominant subtype of 6a [14] [14].
HIV-1 CRF01_AE is the most predominant subtype circulating among sexually acquired cases, where the prevalence of inter-subtype recombinants is relatively very low [ 6].
The most predominant subtype, luminal A, is known to have the best prognosis with HER2 and the basal-like triple negative subtype has the worst outcome [ 77].
A limited number of monoclonal antibodies are generated against the HIV-1 Clade C which is the most predominant subtype worldwide and in India [ 21].
All the HCV patients were infected with HCV genotype 3, of which genotype 3a was the most predominant subtype (68.3%, n= 41) followed by subtype 3b (31.7%, n= 19) (data not shown).
The occurrence and prevalence of SIVs vary among the different regions in Europe but the avian origin H1N1 appears to be the most predominant subtype, followed by reassortant H3N2 and to a lower extent by the H1N2 subtypes, which comprise viruses of diverse genetic constellation [ 1, 11].
Studies performed in both mouse and rat brain tissue have suggested that in particular, the calcium-binding protein known as parvalbumin, and the neuropeptide somatostatin, are two crucial markers in defining the most predominant interneuron subtypes within the cerebral cortex [ 16, 20, 22].
It appears in subtype 6a that is the most predominant HCV subtype circulating in Hong Kong, Hubei and Guangxi.
