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TGFβ is widely regarded as the most powerful inducer of EMT in vitro and in vivo.
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In particular, Tumor Necrosis Factor Alpha (TNF-α) a cytokine endowed with a large repertoire of biological effects is one of the most powerful inducers of the receptor activator of NF-kB ligand (RANKL), i.e. a key trigger of osteoclast activation and bone resorption [ 4- 7].
Music is one of the most powerful mood inducers, provoking immediate affective reactions that can be deduced by looking at human physiology, as in the case of brain cortical activity.
The most potent inducer of VEGF gene expression is hypoxia [23].
IL-1β is the most potent inducer of KGF in fibroblasts.
TGF-β1 is the most potent inducer of matrix synthesis in nucleus pulposus cells.
Sophorose is the most potent inducer for the expression of CBHI and CBHII.
The most potent inducer of cellulase gene expression is α-sophorose.
The most powerful constitutional power was imperium.
MMRi6 and its analogs appeared to be the most potent inducers of p53 protein stabilization.
The cell models, slices, and mainly primary hepatocyte cultures, appear to be the most powerful in vitro systems, as liver-specific functions and responsiveness to inducers are retained either for a few days or several weeks depending on culture conditions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com