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Transition state analogues designed to mimic their cognate transition state structures are among the most powerful enzyme inhibitors.
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This is probably the result of enhanced iNOS activity, the most powerful NO releasing enzyme, which is up-regulated following endothelial activation, such as by ischemia/reperfusion injury or inflammation [27], [28], [29].
The most powerful constitutional power was imperium.
The most effective compound 11d with good enzyme-selectivity exhibited most powerful inhibitory potency against E. coli PDHc-E1 (IC50 = 0.97 μM) and cyanobacteria (EC50 = 0.83 μM).
The third-generation aromatase inhibitors anastrozole, letrozole and exemestane are the most powerful drugs available resulting in approximately 96 99% enzyme inhibition (Dowsett et al, 1995; Geisler et al, 1996, 1998).
It is becoming the most powerful tool for studying uncultured microbes and novel enzymes with biotechnological potential (Duan et al. 2010; Brulc et al. 2009).
The most powerful ones, Glucose BioFuel Cells (GBFCs), are based on enzymes electrically wired by redox mediators.
The protein FruA, an enzyme that breaks apart complex sugars, was the most powerful biofilm blocker.
Also AII stimulates endothelin converting enzyme that degrades big-endothelin releasing endothelin-I, the most powerful vasoconstrictor on vessel walls [ 23- 25].
Economically most powerful?
What's the most powerful?' ".
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