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Compound 9, a nonspecific inhibitor of Na+/K+ ATPase, is the most potent; however, it was also toxic and its IC50 is very close to its minimum lethal concentration, which is likely due to its effect on other cellular targets.
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The most potent bird, however, is hidden deep within the building's bowels.
Currently, inactivated whole-virion EV71 vaccines appear to be the most potent vaccine candidates; however, immunological results are difficult to compare because the standard production methods, standard virus neutralization assays and the methods used to quantify the critical viral antigens are not available.
However, the most potent executioners are still the caspases, particularly caspase-3.
Based on above, methyl matrinates and matrinols exhibited the most potent anti-HCV activities, however, methyl matrinates might not possess favorable PK profiles in vivo owing to the exposed metabolically labile ester group.
The terrorists invoke their faith and its most potent symbols and teachings, however misguided they might be.
The most potent producers of IFNLs however, seem to be myeloid and plasmacytoid dendritic cells (DCs).
However, the most potent designed peptide, DesHDAP1, shares a markedly similar circular dichroism spectrum with buforin II.
However, the most potent analogues only showed moderate activities in a cellular mechanistic assay (42: IC50 = 2.3 μM) together with either low microsomal stability or low permeability.
However, the most potent analogues showed only micromolar activities in an ex vivo glycosaminoglycan (GAG) release assay in bovine cartilage together with low cellular permeability and suboptimal microsomal stability.
However, its most potent impact may have been the way it forced otherwise indifferent observers to recognize the ugliness of the segregation lobby.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com