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Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilators identified to date.
CGRP is one of the most potent endogenous vasodilators and major arteries in the intracranial circulation of man and animals are innervated by CGRP-containing nerve fibers [34 36].
Type 1 17β-hydroxysteroid dehydrogenase (17β-HSD1) is a key steroidogenic enzyme that catalyses the reduction of steroid estrone into the most potent endogenous estrogen estradiol using the cofactor NAD(P H.
UII is considered the most potent endogenous vasoconstrictor discovered to date.
This establishes the Nod proteins as among the most potent endogenous anti-microbial peptides yet identified [15].
TGR5 activity was analyzed using a cAMP-luciferase reporter gene assay following stimulation with TLC, which is the most potent endogenous agonist [36].
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Background Endothelin-1 is the most potent known endogenous vasoconstrictor.
Free radicals are, arguably, considered among the most potent, ubiquitous, endogenous mutagens generated by normal physiological processes (Hussain et al, 2003).
The most potent of these endogenous pyrogens are IL-1 and tumor necrosis factor alpha (TNF-α) [ 16].
Endostatin is one of the most potent and specific endogenous angiogenic inhibitors to enter clinical trials [ 12].
The most prevalent shRNA sequences identified by the CellSelectRNAi approach were the most potent also when measured at endogenous protein level and mRNA level.
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