The diet's most potent component, though, is an occasional serving of what Vonderplanitz calls "high meat".
Conclusions: A mixture of widely used pesticides can, in a predictable manner, produce combined AR antagonist effects that exceed the responses elicited by the most potent component alone.
47 This fraction is enriched with ultrafine particles derived from the combustion of fossil fuels, which toxicology studies have suggested are the most potent component of particulate matter.
The results show that P2 is the most potent component of PTC and demonstrates a favourable activity profile compared with Mel.
This is the first time that a mixture of widely used pesticides has been shown to produce combined AR antagonist effects that exceed the responses elicited by the most potent component alone.
Here, synergisms are pronounced when the mixture effect is greater than that of the most potent component (for recent examples, see Bouslimi et al. 2008; Kocaman and Topaktas 2010).
Asiatic acid, which was identified mainly in EtAcE, is the most potent component of C. asiatica for induction of expression of TNFAIP6, a hyaladherin involved in extracellular matrix remodeling and modulation of inflammation, in human fibroblasts [ 27].
These claims stem from an experimental approach based on comparisons of the effects of the mixture with those of the most toxic component, where synergisms are declared when the mixture effect is larger than the effect of the most potent component.
We assessed combination effects in two ways: First, evaluations in relation to the proliferative responses induced by single mixture components revealed that the combination effects were stronger than the effects of the most potent constituent.
This may be the most potent factor of all.
