Sentence examples for most polymorphic genetic from inspiring English sources

Haplotype inference from data obtained for the 20 most polymorphic genetic variations enabled the identification of 75 different haplotypes.

The histocompatibility leukocyte antigen (HLA) complex, located on chromosome 6p21, is the most polymorphic genetic system in mammals [ 11].

The Major Histocompatibility Complex (MHC), located on chromosome 6p21, is the most polymorphic genetic system in mammalians, and has been studied with regard to a wide variety of diseases of distinct etiology, including infectious diseases.

The MHC is the most polymorphic genetic system known in humans; it is divided into class I (HLA-A, HLA-B, and HLA-C) and class II (HLA-DRB1 and HLA-DQB1) molecules, whose function is to encode membrane glycoproteins that act as mediators in the presentation of antigenic peptides to lymphocytes T CD8+ and T CD4+, respectively, thereby triggering the immune response [ 13].

The major histocompatibility complex (MHC), also known as the human leukocyte antigen (HLA) complex, located on chromosome 6p21.3, is the most polymorphic genetic system in mammalians and has been studied with regard to a wide variety of diseases of distinct etiology.

In the age of next-generation sequencing, microsatellites remain the most polymorphic and informative genetic marker for inferring species population genetics.

The HLA system is the most polymorphic of all human genetic systems and this diversity raises a substantial challenge in the identification of matched donors.

We performed linkage analysis in the core family using highly polymorphic genetic markers around the most likely candidate genes, ELANE, CSF3R, GFI1 and CSF3.

Recent genome-wide association studies of HIV-1 clade B exposed cohorts have confirmed that HLA-B, which is the most polymorphic locus in the human genome, is the major genetic locus contributing to immune control of viraemia.

These difficulties in understanding the MHC are not without reason; it contains some of the most polymorphic loci described in the genome, and has a highly complicated genetic architecture, with some regions exhibiting extended linkage disequilibrium [ 13].

The CYP21A2 gene, localized in a genetic unit defined RCCX module, is considered one of the most polymorphic of human genes.