The Major Histocompatibility Complex (MHC) includes the most polymorphic genes in vertebrates [ 1].
The HLA gene complex is different from other genomic regions by harbouring the most polymorphic genes we know; isotypic and allotypic polymorphism is in fact central to the physiological role of the class I and class II molecules.
Major histocompatibility complex (MHC) genes are the most polymorphic genes found in vertebrates, having hundreds of alleles in human populations and, generally, dozens of alleles in other vertebrate species (reviewed in [ 1- 4]).
The human TNF gene is located within the most polymorphic region of the human genome, the major histocompatibility complex (MHC) region of chromosome 6, which includes the human leukocyte antigen (HLA) genes [10].
The major histocompatibility complex (MHC) is one of the most polymorphic regions in the vertebrate genome [ 1, 2].
The major histocompatibility complex (MHC) is one of the most polymorphic regions in human as well as in nonhuman primates and other mammal species studied.
The histocompatibility leukocyte antigen (HLA) complex, located on chromosome 6p21, is the most polymorphic genetic system in mammals [ 11].
The major histocompatibility complex (MHC), also known as the human leukocyte antigen (HLA) complex, located on chromosome 6p21.3, is the most polymorphic genetic system in mammalians and has been studied with regard to a wide variety of diseases of distinct etiology.
The Major Histocompatibility Complex (MHC), located on chromosome 6p21, is the most polymorphic genetic system in mammalians, and has been studied with regard to a wide variety of diseases of distinct etiology, including infectious diseases.
The major histocompatibility complex (MHC) genes coding for antigen presenting molecules are the most polymorphic genes in vertebrate genome.
