In total, 18 candidates were considered as the most plausible genes of weeping in the casual region (Fig. 6B).
Changing alternator load is the most plausible factor in piston or displacer exceeding the displacement limit.
This provides further evidence that gene-calling error may account for most of the inconsistencies in groups 1 to 4, whereas true evolutionary divergence is the most plausible factor for group 5.
Nevertheless, this result is in agreement with a previous study that also showed lower expression of the LPP gene in biopsies of CeD patients (20), suggesting that LPP is the most plausible causative gene in this locus.
The most plausible candidate genes for the acylation, Pun1, and the putative aminotransferase gene, pAMT, have been highly correlated with capsaicinoid accumulation in several genetic studies of mutant alleles that corresponded to either pAMT or Pun1 [ 13, 18, 19].
The most plausible candidate genes are components of the renin angiotensin aldosterone system and genes involved in signal transduction (e.g. the G-protein subunit-β3 gene GNB3), salt and water handling (e.g. the adducin-α genes ADD1), regulation of vascular tone (e.g. the endothelial nitric oxide synthase gene NOS3) and production of or defences against oxidative stress.
However, sequencing the three most plausible candidate genes in this region— DLX5, DLX6 and DSS1 failed to reveal mutations.
Integrated analysis of transcriptome profiling, QTL mapping and comparative genomics with other relative species leads to efficient identification of most plausible functional genes underlying oil-content related characters, offering valuable resources for bettering breeding program of Brassica napus.
Disease gene prediction, the task of identifying the most plausible candidate disease genes, is an important issue in biomedical research and many studies have been done for this [1, 2].
