The use of shorter peptides indicated that the minimum peptide epitopes for these MAbs were different.
Only 58 of the 835 (6.9%) transcripts showed signal peptides, indicating that most were involved in intracellular processes in contrast to the salivary glands, where a much higher proportion (29%) comprised secreted proteins [ 77, 78].
Conversely, most HLA-DR molecules bound to at least 10 of the peptides, indicating that an individual bearing at least one such HLA-DR molecule could develop broad CD4+ T cell responses against the HIV-1 peptide set [32].
This indicated that most peptides were being identified in multiple samples across time points rather than an overrepresentation of a few technical replicate samples.
Although most peptides were expressed at similar levels in WT and CS samples, the SD was larger for this pair, indicating that peptides whose abundance differed between WT and CS were present (Fig. 2C).
Most peptides today are manufactured by solid-phase peptide synthesis (SPPS).
The most peptides came from SCG2 (3 peptides), CART prepropeptide (CARTPT) (3 peptides), PEBP1 (2 peptides), peroxiredoxin 5 (peptides2 peptides), and PCSK1N (2 peptides).
The lowercase letters in the peptide indicate SAPs.
Moreover, the bio-peptide indicates potential immunomodulatory effect.
Proteotypic peptides are those peptides that most strongly indicate the presence of a target protein in a sample.
