Trivariate models were also evaluated using the clinically most optimal sample-time points (i.e. 1, 190 and 360 h post-infusion).
Using the most optimal sampling interval (5 breaths), a change of at least 13 s in τ is needed to exceed normal test-to-test variations.
A major role for imaging is to direct the most optimal method of tissue sampling in order to establish the highest possible tumor stage, so that proper therapy may be instituted [ 1].
The 250-m point sampling strategy proved most optimal because it oversampled the landscape relative to the geostatistical range of actual spatial variation, as indicated by the sample semivariograms, while making the sample data volume more manageable.
Additionally, our search may not have employed the most optimal keywords to generate an ideal sampling from around the world.
Laser ablation of the sample using 7.2 mJ proved to be the most optimal, and the precision of measurement calculated as %RSD was 4%.
Then, can such a generator be used to answer the "best-practice" questions about the population: what is the (1) optimal sample size and (2) optimal sequence length for the most informative analysis.
Given the characteristics of a population, possibly derived from observed extant individuals, to estimate the (1) optimal sample size and (2) optimal sequence length for the most informative analysis.
In terms of reproducibility, the most optimal method to characterize O2 recovery kinetics was mono-exponential modeling with sampling intervals of 5 breaths (intra-class correlation 0.94).
To include patients for symptom registration, and not only blood samples, prior to the first treatment had been the most optimal.
However, to fully inform the research decision, the most efficient research design also needs to be established, for example, the type of study, the optimal sample size, the appropriate duration of follow-up and appropriate end points.
