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HumDiv aims to identify alleles that may alter protein function, while HumVar aims to discriminate variants with large effects (sufficient to cause Mendelian disease) from alleles that are at most only mildly deleterious.
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Slightly more than half of the sample had bipolar disorder (i.e., 59.8% had bipolar disorder and 40.2% had depressive disorder) with relatively high GAF scores (62.7 ± 14.7) suggesting most were only mildly to moderately impaired.
Much of the Andes, for instance, consists of sedimentary rock that never was buried deeper than a few kilometres and therefore has not been metamorphosed (heated to high temperature or put under high pressure) or at most only has been mildly metamorphosed.
The other 36 picks–real value stocks all for the most part suffered only mildly.
Drug firms have been working on them for decades as part of an effort to come up with new asthma medications, but most were abandoned as only mildly effective.
For example, most symptomatic patients have only mildly stenotic lesions [ 2].
In the first study, where most intersex fish were only mildly feminized, body length was the only factor correlated with reproductive success.
In this study, the ALT/AST concentrations were very high at 24 h time point, however, those surviving mice with high ALT/AST levels did not look severely ill, most of them looked only mildly distressed.
This last is a scene that is routinely cited as one of Shakespeare's most moving, yet is often only mildly impressive.
Among the highlights, "A Season with Eros" is a hilariously candid account of newlywed passion doused by a sour-faced mother-in-law, while the hooligan protagonist of "The Desperadoes" ("Sometimes you feel you just can't rest until you've smashed summat") is a reminder that Barstow's fury made most other angry young men seem only mildly annoyed.
It boasts new textured grips and new thumbstick designs, but most of the physical changes are only mildly noticeable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com